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Appendix 2: Drugs Covered by the Program - Page 5

Note: Drugs funded under the Highly Specialised Drugs Program provide a subsidy for community patients only. Inpatients remain the responsibility of the treating hospital.

Page 1 Abacavir Sulfate with Lamivudine (Kivexa) to Baclofen (Lioresal Intrathecal)
Page 2 Boceprevir (Victrelis) to Bosentan Monohydrate (Tracleer)
Page 3 Cidofovir (Vistide) to Epoetin lamda (Novicrit)
Page 4 Epoprostenol Sodium (Flolan)
Page 5 Etanercept (Enbrel) to Ibandronic Acid (Bondronat)
Page 6 Iloprost Trometamol (Ventavis) to Indinavir Sulphate (Crixivan)
Page 7 Infliximab (Remicade) to Sevelamer (Renagel)
Page 8 Sildenafil Citrate (Revatio)
Page 9 Sirolimus (Rapamune) to Zoledronic acid (Zometa)

Drug

Date Subsidised

PBAC Clinical Indications and other Restrictions

Etanercept (Enbrel)

 

1 April 2005

Revised 1 November 2009

Revised 1 November 2010

Public hospital authority required

This drug needs prior approval by Medicare Australia, more information and forms are available at http://www.medicareaustralia.gov.au/provider/pbs/highly-specialised-drugs/complex-authority-drugs.jsp
 

PDF Icon Etanercept - November 2010 (pdf, 258kb)

Etravirine (Intelence)

1 July 2009

Amended 1 January 2011

Treatment of HIV infection, in addition to optimised background therapy in combination with other antiretroviral agents in an antiretroviral experienced patient who, after each of at least three different antiretroviral regimens that have included one drug from at least 3 different antiretroviral classes, has experienced virological failure or clinical failure or genotypic resistance.

Virological failure is defined as a viral load greater than 400 copies per mL on two consecutive occasions, while clinical failure is linked to emerging signs and symptoms of progressing HIV infection or treatment –limiting toxicity. (3597)
Everolimus (Certican) 1 August 2005

CAUTION:
Careful monitoring of patients is mandatory.

Management of rejection, under the supervision and direction of a transplant unit, in patients receiving this drug for prophylaxis of renal allograft rejection. Management includes initiation, stabilisation and review of therapy as required; (3355)
Management of rejection, under the supervision and direction of a transplant unit, in patients receiving this drug for prophylaxis of cardiac allograft rejection. Management includes initiation, stabilisation and review of therapy as required. (3356)

Filgrastim (Neupogen, Nivestim, TevaGrastim)

1 September 1993

Revised Feb 2002

Amended 1 March 2008

Amended 1 July 2008

Amended 1 February 2009

Amended 1 April 2009

Amended 1 October 2009

Amended 1 September 2011

Amended 1 March 2012

For use in a patient undergoing induction and consolidation therapy for acute myeloid leukaemia; (3357)

Mobilisation of peripheral blood progenitor cells to facilitate harvest of such cells for autologous transplantation into a patient with a non-myeloid malignancy who has had myeloablative or myelosuppressive therapy; (3358)

Mobilisation of peripheral blood progenitor cells, in a normal volunteer, for use in allogeneic transplantation; (3359)

A patient receiving marrow-ablative chemotherapy and subsequent bone marrow transplantation; (3360)

A patient with a non-myeloid malignancy receiving marrow-ablative chemotherapy and subsequent autologous peripheral blood progenitor cell transplantation; (3361)

A patient with breast cancer receiving standard dose adjuvant chemotherapy who has had a prior episode of febrile neutropenia or prolonged severe neutropenia (neutrophil count of less than 1,000 million cells per litre), and for whom there is clinical justification for wishing to continue therapy with the same drug combination, dosage and treatment schedule, and for whom a good response to treatment is anticipated providing chemotherapy can be delivered as planned; (3362)

A patient receiving chemotherapy for B-cell chronic lymphocytic leukaemia with fludarabine and cyclophosphamide who has had a prior episode of febrile neutropenia or prolonged severe neutropenia (neutrophil count of less than 1,000 million cells per litre), and for whom there is clinical justification for wishing to continue therapy with the same drug combination, dosage and treatment schedule, and for whom a good response to treatment is anticipated providing chemotherapy can be delivered as planned; (3363)

A patient receiving first-line chemotherapy for Hodgkin's disease who has had a prior episode of febrile neutropenia or prolonged severe neutropenia (neutrophil count of less than 1,000 million cells per litre), and for whom there is clinical justification for wishing to continue therapy with the same drug combination, dosage and treatment schedule, and for whom a good response to treatment is anticipated providing chemotherapy can be delivered as planned; (3364)

A patient receiving chemotherapy for myeloma who has had a prior episode of febrile neutropenia, and for whom there is clinical justification for wishing to continue therapy with the same drug combination, dosage and treatment schedule, and for whom a good response to treatment is anticipated providing chemotherapy can be delivered as planned; (3365)

A patient with severe congenital neutropenia (absolute neutrophil count of less than 100 million cells per litre measured on 3 occasions, with readings at least 2 weeks apart, and in whom a bone marrow examination has shown evidence of maturational arrest of the neutrophil lineage); (3366)

A patient with severe chronic neutropenia (absolute neutrophil count of less than 1,000 million cells per litre measured on 3 occasions, with readings at least 2 weeks apart, or evidence of neutrophil dysfunction, and, either having experienced a life-threatening infectious episode requiring hospitalisation and treatment with intravenous antibiotics in the previous 12 months, or having recurrent clinically significant infections (a minimum of 3 in the previous 12 months)); (3367)

A patient with chronic cyclic neutropenia (absolute neutrophil count of less than 500 million cells per litre lasting for 3 days per cycle, measured over 3 separate cycles, and, either having experienced a life-threatening infectious episode requiring hospitalisation and treatment with intravenous antibiotics, or having recurrent clinically significant infections (a minimum of 3 in the previous 12 months)). (3368)

A patient with inoperable Stage III, IVa or IVb squamous cell carcinoma of the oral cavity, larynx, oropharynx or hypopharynx receiving neoadjuvant treatment with docetaxel in combination with cisplatin and fluorouracil who has had a prior episode of febrile neutropenia or prolonged severe neutropenia (neutrophil count of less than 1,000 million cells per litre), and for whom there is clinical justification for wishing to continue therapy with the same drug combination, dosage and treatment schedule, and for whom a good response to treatment is anticipated providing chemotherapy can be delivered as planned. (3369)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in Acute lymphoblastic leukaemia; (3370)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in breast cancer (adjuvant chemotherapy with docetaxel in combination with an anthracycline and cyclophosphamide); (3371)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in germ cell tumours; (3372)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in infants and children with CNS tumours; (3373)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in neuroblastoma; (3374)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in non-Hodgkin's lymphoma (aggressive grades; or low grade requiring an anthracycline-containing regimen); (3375)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in relapsed Hodgkin's disease; (3376) A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in sarcoma (3377)

A patient being treated with aggressive chemotherapy with the intention of achieving a cure or substantial remission in Hodgkin disease (first-line chemotherapy with escalated BEACOPP) (3834)

Fosamprenavir Calcium (Telzir )

1 December 2004

Amended 1 January 2011

Initial treatment of HIV infection in combination with other antiretroviral agents in a patient with a CD4 count of less than 500 per cubic millimetre or symptomatic HIV disease (3588)

Continuing treatment of HIV infection in combination with other antiretroviral agents where the patient has previously received PBS-subsidised therapy for HIV infection (3589)
Foscarnet Sodium (Foscavir)

1 Mar 1994

Revised
Nov 2002

Treatment of cytomegalovirus retinitis in patients with AIDS; (3322)

Treatment of aciclovir resistant herpes simplex virus infection in immunocompromised patients with HIV infection. (3378)

Ganciclovir (Cymevene)
(Vitrasert)

Revised
Nov 2002

Amended 1 February 2004

Revised December 2005

Ganciclovir (Vitrasert intravitreal implant)
Cytomegalovirus retinitis in severely immunocompromised patients; (3379)

Ganciclovir Sodium (Cymevene powder forIV infusion)
Cytomegalovirus retinitis in severely immunocompromised patients; (3379)
Prophylaxis of cytomegalovirus disease in bone marrow transplant patients at risk of cytomegalovirus disease;(3380)
Prophylaxis of cytomegalovirus disease in solid organ transplant patients at risk of cytomegalovirus disease. (3381)

Ibandronic Acid (Bondronat)

1 March 2008

Bone metastases from breast cancer (3343)

Page 6 >>

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